Preheat the oven to 350 degrees and prepare a large casserole dish by spraying with nonstick cooking spray.

Cook pasta according to package directions. Drain and set aside.

Brown ground beef in a large skillet with diced onion and chopped garlic. Remove from heat and drain of excess fat.

Mix in marinara sauce and cooked pasta.

In a medium bowl, combine ricotta cheese, cream cheese, one cup of mozzarella cheese, Italian seasoning, and garlic powder. Stir to combine.

Place a layer of pasta mixture in the bottom of the casserole dish.

Top with a layer of cheese mixture.

Continue layering until all ingredients have been used.

Top final layer with remaining mozzarella cheese.

Bake for 20 minutes or until cheese is melted and sauce is bubbly.